Creation, Evolution, and Cystic Fibrosis (Part Two)

by Navy Christian

This post represents the conclusion to the previous post on my initial cystic fibrosis genetic evolution research.

Tuberculosis (TB) is another “underappreciated” option.[1] This is the closest of all options in actually being the evolutionary cause of cystic fibrosis. TB occurs in the right geographical area, thus it can pass that part of the test, though I submit that the data does not show it passing the historical method because most research is from historical models as recently as the 1600s. That doesn’t mean that heterozygote CF carriers don’t possess an advantage in not contracting TB. It just means that it is too recent a development to be the cause of CF mutations.

So while I can accept that TB presents the best case for evolution as it relates to cystic fibrosis, it has a significant issue. The study points to the epidemic of the 17th century in Europe as evidence that CF has an evolutionary heritage associated with the disease. CF has been around for 50,000 years, according to scientists. Researchers don’t know the exact age of TB (estimated to be roughly 40,000 years old), but I’ve yet to find anywhere that suggests it’s as old as CF. By their own research, CF cannot come from nature’s response to TB. At best, the research points to its prevention of TB as a happy accident.

In short, either CF is much younger than first thought or it isn’t nature’s response to TB.

Natural Selection’s Failure

The reality is that, as of current research, CF has no known cause outside of the religious contention that it was caused by the fall of man. So, since it has no provable cause, nature should have been able to eradicate it. Yet it hasn’t, and only recently has any eradication occurred at all, and a very small percentage at that.

Here’s why CF wasn’t eradicated by natural selection: Nature can’t eradicate recessive genes. They can lie dormant for generations. I have no known deaths in my familial history from cystic fibrosis, yet I have a daughter with cystic fibrosis, so I am a carrier. Only God knows how long it’s been sitting in some part of my family tree, dormant, until produced with another like mutation in the life of our daughter.

In the next post, I will be following up my research with some thoughts on the age of cystic fibrosis. Sign up HERE to stay up to date with this research.

[1] Poolman, Eric M, and Alison P Galvani. “Evaluating Candidate Agents of Selective Pressure for Cystic Fibrosis.” Journal of the Royal Society Interface4.12 (2007): 91–98. PMC. Web. 21 Nov. 2015.

 

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